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Integrin beta 4 抗体

This anti-Integrin beta 4 antibody is a 大鼠 单克隆 antibody detecting Integrin beta 4 in WB, FACS, IHC (fro) 和 IHC (p). Suitable for 人.
产品编号 ABIN614431
发货至: 中国

Quick Overview for Integrin beta 4 抗体 (ABIN614431)

抗原

See all Integrin beta 4 (ITGB4) 抗体
Integrin beta 4 (ITGB4)

适用

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宿主

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大鼠

克隆类型

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单克隆

标记

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This Integrin beta 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

439-9B
  • 特异性

    Recognizes Integrin Beta 4 (ITGB4).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography.

    免疫原

    Human ITGB4

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2 containing < / = 0.09 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    Integrin beta 4 (ITGB4)

    别名

    CD104 / Integrin beta-4

    背景

    Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits. The 16 alpha and 8 beta subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.Synonyms: GP150, ITGB4

    基因ID

    3691

    NCBI登录号

    NP_000204

    UniProt

    P16144

    途径

    Integrin Complex
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